Capturing Real-Time Structural Snapshots of Functional Biomolecules and Materials

Using state-of-the-art vibrational spectroscopic tools developed by great minds across the world, we have obtained unprecedented precision both in the spatial and temporal domain to tackle one of the most intriguing questions in life sciences: how do biomolecules functionalize? As a bottom-up approach for future bioengineering advances and biomedicine breakthroughs, ultrafast laser spectroscopy will enable us to get down to the time regime where intrinsic molecular motions & conformational dynamics are dominant and functional, to unveil the magic from bioluminescence to protein folding to drug potency, and to appreciate the fundamental physics and chemistry principles in play. Recently, we have ventured into material sciences and uncovered the mechanism for aluminum (Al) speciation in water.

From left: Sean Tachibana, Cheng Chen, Longteng Tang, Chong Fang, Liangdong Zhu, Taylor Krueger, and Sean Boulanger (May 2019). Not pictured: Nikita Rozanov, Travis Seevers, Jose Ceja, and Eli Schaffer. Outside Linus Pauling Science Center. Check more...

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